The mAb anti-Human alpha1-antitrypsin Antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human antigen. The mAb anti-Human alpha1-antitrypsin Antibody has been validated for the following applications: Western Blot.
Description
Description: Mouse monoclonal antibody to human alpha1-antitrypsin
background: alpha1-antitrypsin is a protective protease inhibitor. It inhibits elastase released by neutrolphils during inflammatory reaction and irreversibly inactivates trypsin secreted in duodenum and else where. alpha1-antitrypsin normally presents in plasma at 1.5-3.5 mg/mL, but increases in acute phase reaction, malignancies, pregnancy and trauma. Severe hereditary alpha1-antitrypsin deficiency can result in damages to alveoli, chronic obstructive pulmonary disease (COPD), and liver diseases such as jaundice and cirrhosis. The protein is also found in the neurofibrillary tangles and senile plaques in the brain lesions of Alzheimer's disease. Whether or not it contributes to the pathology of Alzheimer's disease is not confirmed